Symbol
Name
ID

Plxnd1
plexin D1
MGI:2154244

Phenotype annotations related to cardiovascular system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

cardiovascular system phenotype

abnormal blood vessel morphology

abnormal artery morphology

abnormal fourth pharyngeal arch artery morphology

abnormal sixth pharyngeal arch artery morphology

abnormal aorta morphology

aberrant origin of the right subclavian artery

right aortic arch

vascular ring

abnormal ascending aorta and coronary artery attachment

abnormal left subclavian artery morphology

increased capillary density

abnormal retina vasculature morphology

abnormal induced retina neovascularization

abnormal intersomitic vessel morphology

abnormal lung vasculature morphology

decreased angiogenesis

increased angiogenesis

absent fetal ductus arteriosus

abnormal vascular endothelial cell migration

abnormal vascular smooth muscle morphology

abnormal pulmonary vein morphology

abnormal inferior vena cava morphology

dual inferior vena cava

abnormal myocardium layer morphology

abnormal ventricle myocardium morphology

thin myocardium

abnormal truncus arteriosus septation

persistent truncus arteriosus

persistent truncus arteriosus type i

persistent truncus arteriosus type ii

abnormal coronary vessel morphology

abnormal coronary sinus connection

double outlet right ventricle

abnormal heart atrium morphology

increased heart atrium size

atrial septal defect

common atrium

atrium cyst

dilated heart atrium

atrioventricular septal defect

complete atrioventricular septal defect

ventricular septal defect

detached epicardium

hemorrhage

intracranial hemorrhage

subcutaneous hemorrhage

Availability

Mouse Genotype

Plxnd1^b2b553Clo/Plxnd1^b2b553Clo

Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo

Plxnd1^b2b3150Clo/Plxnd1^b2b3150Clo

Plxnd1^em1Zho/Plxnd1^em1Zho

Plxnd1^tm1Ddg/Plxnd1^tm1Ddg

Plxnd1^tm1Joe/Plxnd1^tm1Joe

Plxnd1^em1Zho/Plxnd1⁺

Plxnd1^tm1.1Tmj/Plxnd1^tm1.1Tmj
Tg(Tek-cre)1Ywa/0 (conditional)

Plxnd1^tm1.1Tmj/Plxnd1^tm1.1Tmj
H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)

Plxnd1^tm1.1Tmj/Plxnd1^tm1.1Tmj
Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Plxnd1^tm1Ddg/Plxnd1^tm1.1Tmj
Tg(CAG-cre/Esr1*)1Egwa/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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